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Background: CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a polyclonal antibody directed against the epsilon chain of human CD3 molecule.

Host species/Isotype:Rabbit/IgG

Cross reaction: Human

Immunogen: CD3 fusion protein .

Storage instructions:Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Concentration: 330ug/ml

Purity:Antigen affinity purification

Clonality:Polyclonal

Tested applications: 

WB : 1:500-1:3000

IP : 0.5-4.0 ug

IHC : 1:20-1:200