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Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Catalog Number : GS-21495a

Specification : 100ul

Host species/Isotype : Rabbit/IgG

Cross reaction : Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig

Immunogen :KLH conjugated synthetic peptide derived from human ACTA1

Storage instructions: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Concentration : 1mg/ml

Purity : affinity purified by Protein A

Clonality : Polyclonal

Molecular weight: 42KDa

Tested applications:

ELISA=1:500-1000

IHC-P=1:100-500

IHC-F=1:100-500

ICC=1:100-500

IF=1:100-500