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CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products
Synonyms: | caspase a |
Attribute: | Rabbit Polyclonal Antibody |
Isotype: | Polyclonal |
Purity: | Antigen Affinity Purification |
Application: | ELISA, WB, IP |
Calculated MW: | 44kDa |
Observed MW: | 10+20+30+44kDa |
Reactivity： | Zebra fish |
Immunogen： | Peptide corresponding to zebra fish caspase-1 |
Buffer： | PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 |
Storage: | Store at -20℃. Do not aliquot |
Recommended Dilution: | WB: 1:1000-2000 IP: 1:5000-10000 IF: 1:100-200 |
產(chǎn)品貨號：gs62101
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