Adipogen/GITR (human):Fc (human) (rec.)/AG-40B-0028-C050/50 ?g
重組蛋白
商品編號
AG-40B-0028-C050
品牌
Adipogen
公司
Adipogen
公司分類(lèi)
Proteins
Size
50 ?g
商品信息
More Information
Product Details
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR; Activation-induc
IBL
e TNFR Family Receptor
Product Type
Protein
Properties
Source/Host
HEK 293 cells
Sequence
Human GITR (aa 26-162) is fused at the C-terminus to the Fc portion of human IgG1.
Crossreactivity
Human
Specificity
Binds to human GITRL.
MW
~48kDa (SDS-PAGE)
Purity
≥95% (SDS-PAGE)
Endotoxin Content
<0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu>
Concentration
1mg/ml after reconstitution.
Reconstitution
Reconstitute with 50μl sterile water.
Formulation
Lyophilized. Contains PBS.
Other Product Data
UniProt link Q9Y5U5
GITR (human)
Shipping and Handling
Shipping
BLUE ICE
Short Term Storage
+4°C
Long Term Storage
-20°C
Handling Advice
After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/St
ABI
lity
Stable for at least 6 months after receipt when stored at -20°C.
Documents
MSD
S
Download PDF
Product Specification Sheet
Datasheet
Download PDF
GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-κB activation via the TRAF2/NIK pathway.
產(chǎn)品貨號:3484.0