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商品編號(hào)


AG-40B-0008-3010



品牌


Adipogen



公司


Adipogen



公司分類


Proteins



Size

3 x 10 ?g


商品信息


More Information



Product Details



Synonyms

TRANCE; ODF; OPGL; TNFSF11; CD254



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Human RANKL (aa 152-317) is fused at the N-terminus to a FLAG
?
-tag.



Crossreactivity

Human
Mouse



Specificity

Binds to human and mouse RANK.



MW

~28kDa (SDS-PAGE)



Purity

≥95% (SDS-PAGE)



Endotoxin Content

<0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu>



Concentration

0.1mg/ml after reconstitution.



Reconstitution

Reconstitute with 100μl sterile water.



Formulation

Lyophilized. Contains PBS.



Other Product Data

UniProt link O14788: RANKL (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0.1% BSA should be used for further dilutions.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





RANKL is an osteoclast differentiation and activation factor. Augments the
ABI
lity of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of breast cancer.