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商品編號(hào)


AG-40A-0010Y-C050



品牌


Adipogen



公司


Adipogen



公司分類


Proteins



Size

50 ?g


商品信息


More Information



Product Details



Synonyms

FIZZ3; Found in Inflammatory Zone 3; ADSF;
ADI
pose Tissue-Specific Secretory Factor



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Human resistin (aa 19-108) is fused at the N-terminus to a FLAG
?
-tag.



Crossreactivity

Human



BIOLOG
ical Activity

Inhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells.



MW

~13kDa (SDS-PAGE)



Purity

≥95% (SDS-PAGE)



Endotoxin Content

<0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu>



Concentration

After reconstitution:
for 10?g size:
0.1mg/ml
for 50?g size:
1 mg/ml



Reconstitution


10?g size:
Reconstitute with 100?l sterile water.
50?g size:
Reconstitute with 50?l sterile water.
PBS containing at least 0.1% BSA should be used for further dilutions.



Formulation

Lyophilized. Contains PBS.



Other Product Data


UniProt link Q9HD89: Resistin (human) (precursor)

FLAG is a registered trademark of
Sigma-Aldrich
Co.




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0.1% BSA should be used for further dilutions.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





The
ADI
pocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-α/FIZZ 1 and RELM-β/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits
ADI
pogen
esis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an
ADI
pocyte-secreted factor thought to link obesity and T2DM.


Product References
Expression of resistin in the prostate and its stimulatory effect on prostate cancer cell proliferation: H.J. Kim, et al.; BJU Int.
108:
1464 (2010)